Once a surgery date is set, the last thing many people sort out is the medicine they take every day. When a blood pressure pill and a drug for benign prostatic hyperplasia (BPH) sit in the same pouch, it is easy to fall into an all-or-nothing question: should everything be stopped, or should everything continue? In practice, preoperative medication is not decided as one bundle. Each ingredient is judged on its own, which is why five pills often split into four continued and one paused a couple of days ahead.

The first axis is the risk of stopping. Some medicines, such as long-term beta-blockers, are associated with rebound increases in heart rate and blood pressure when they are abruptly withdrawn, so they are commonly continued up to the morning of surgery. Stopping on one's own 'just to be safe' can leave blood pressure unstable the day before and delay the schedule.

The second axis is how a drug behaves under anesthesia. Angiotensin-converting enzyme inhibitors (ACE inhibitors) and angiotensin receptor blockers (ARBs) may contribute to an excessive drop in blood pressure at induction, so some centers instruct patients to skip the morning dose. Diuretics may be adjusted because of dehydration and electrolyte shifts, and certain diabetes medicines are paused days in advance for metabolic reasons. What matters is the drug class, not the brand name or the color of the tablet.

The third axis is the operation itself. Alpha-blockers used for BPH have been linked to intraoperative floppy iris syndrome (IFIS) during eye surgery, particularly cataract surgery, so both current and past use should be reported in advance to an ophthalmic team. For many abdominal or orthopedic procedures these drugs are often continued, with attention to dizziness or postural blood pressure drops when they overlap with antihypertensives. Antiplatelet and anticoagulant drugs, herbal products and supplements form a separate track and need their own review.

A workable order is this. First, keep the pharmacy labels and prescriptions, or photograph them, so that ingredient, dose and timing are visible in one list. Second, confirm the preoperative anesthesia consultation and show the entire list at once. Third, write down for each drug whether it is continued or held, how many days beforehand if held, and whether it may be swallowed with a small sip of water during fasting. Fourth, if the prescribing clinic and the surgical center differ, ask who makes the final call. Fifth, ask when each drug resumes after the operation.

If surgery is only days away, calling the department is better than waiting. This article is general information and does not replace medical care. Decisions about continuing or stopping any medication should be made with your own clinical team.